Craniofacial Fibrous Dysplasia Involving the Paranasal Sinuses: A Case Report

Displasia fibrosa craneofacial con compromiso de senos paranasales: Reporte de caso

Authors

  • Carlos Alfredo Iñiguez Guzmán Scanner Cuenca Corp
  • Joel Sebastian Vintimilla Contreras Universidad Católica de Cuenca

DOI:

https://doi.org/10.22258/hgh.v10i3.441

Abstract

Fibrous dysplasia is a benign, congenital bone disorder in which normal medullary bone is progressively replaced by immature fibro-osseous tissue. Although biologically benign, craniofacial involvement can clinically and radiologically mimic destructive neoplasms due to its capacity to expand into the paranasal sinuses. We report the case of a 22-year-old female presenting with chronic left nasal obstruction and diffuse facial pain. Computed tomography of the paranasal sinuses revealed a homogeneous, expansive endoosseous lesion with characteristic ground-glass density (411 HU) involving the frontal sinus, ethmoid, sphenoid, crista galli, and left orbital wall, which caused a reactive severe "italic S" septal deviation. An endoscopic decompressive biopsy was performed. Histopathological examination confirmed a fibro-osseous proliferation composed of irregular, curvilinear immature bone trabeculae arranged in a "Chinese characters" pattern within a uniform fibrous stroma, characterized by the diagnostic absence of osteoblastic rimming and cellular atypia. The close correlation between the non-destructive expansive tomographic pattern and classic histological findings established the diagnosis, ruling out osteosarcoma and supporting conservative management. Anatomoradiological recognition of this multisinusal entity prevents unnecessary radical surgical interventions. Keywords: Diagnosis, Differential; Fibrous Dysplasia of Bone; Histology; Paranasal Sinuses; Tomography, X-Ray Computed. (Source: MeSH, NLM).

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Author Biographies

Carlos Alfredo Iñiguez Guzmán, Scanner Cuenca Corp

Médico Especialista en Imagenología en Cuenca, Ecuador.

Joel Sebastian Vintimilla Contreras, Universidad Católica de Cuenca

Rotating Medical Intern at Hospital de Especialidades Eugenio Espejo, from Universidad Católica de Cuenca. Founder of the Medical Interns Research Committee of the Hospital de Especialidades Eugenio Espejo (CIM-HEE).

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Published

2026-09-15

How to Cite

Iñiguez Guzmán, C. A., & Vintimilla Contreras, J. S. (2026). Craniofacial Fibrous Dysplasia Involving the Paranasal Sinuses: A Case Report: Displasia fibrosa craneofacial con compromiso de senos paranasales: Reporte de caso. Peruvian Journal of Health Care and Global Health, 10(3). https://doi.org/10.22258/hgh.v10i3.441

Issue

Vol. 10 No. 3 (2026)

Section

Case reports

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Copyright (c) 2026 Carlos Alfredo Iñiguez Guzmán, Joel Sebastian Vintimilla Contreras

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