Time Series of Reported Morbidity in Mexico, 2000–2024, Using the National Epidemiological Bulletin
Serie temporal de morbilidad notificada en México, 2000–2024, con el Boletín Epidemiológico Nacional
DOI:
https://doi.org/10.22258/hgh.v10i2.403Abstract
Objectives. To reconstruct and describe the dynamics of reported morbidity in Mexico (2000–2024) based on available and validated official data, and to identify long-term trends, epidemic cycles, and temporal disruptions useful for epidemiological analysis, integrated surveillance, and public health decision-making. Materials and Methods. A descriptive, documentary, and longitudinal study based on the National Epidemiological Bulletins at the annual close of surveillance (weeks 52/53), 2000–2024. Twelve groups were selected, including communicable diseases, non-communicable diseases (NCDs), and psychosocial events. Annual case series were reconstructed, and normalized indices (base year 2000) were calculated to compare trajectories across groups. Results. Acute respiratory infections and intestinal infectious diseases remained the leading causes of morbidity, increasing until 2019, followed by a sharp decline in 2020 and a rebound in 2022–2024. Dengue showed a cyclical pattern with peaks in 2007–2009, 2012–2013, 2019, and 2024. In contrast, diabetes mellitus and arterial hypertension exhibited sustained cumulative growth, with acceleration since 2015. Depression and intrafamily violence increased from 2015 onward, with an inflection point during the COVID-19 pandemic. Conclusion. Between 2000 and 2024, Mexico exhibited a heterogeneous epidemiological transition characterized by the persistent overlap of communicable diseases, expanding NCDs, and an emerging psychosocial burden. Longitudinal reconstruction using official bulletins, through time series and normalized indices, provides a replicable resource for epidemiological analysis, integrated surveillance, and strengthening public health decision-making. Keywords: Epidemiological Monitoring; Morbidity; Health Transition; Communicable Diseases; Noncommunicable Diseases; Mexico (Source: MeSH, NLM).Downloads
References
Barquera S, Hernández-Barrera L, Trejo B, Shamah T, Campos-Nonato I, Rivera-Dommarco J. Obesidad en México: prevalencia y tendencias en adultos. Ensanut 2018–19. Salud Publica Mex. 2020;62(6):682–692. DOI:10.21149/11630.
Basto-Abreu AC, López-Olmedo N, Rojas-Martínez R, Aguilar-Salinas CA, De la Cruz-Góngora VV, Rivera-Dommarco J, et al. Prevalence of diabetes and glycemic control in Mexico: national results from 2018 and 2020. Salud Publica Mex. 2021;63(6):725–733. DOI:10.21149/12842.
Razo C, Lozano R, Gutiérrez-Robledo LM. La carga de la enfermedad en los adultos mayores en México, 1990–2022: tendencias y desafíos para el sistema de salud. Gac Med Mex. 2024;160(6):543–552. DOI:10.24875/GMM.24000209.
Gutiérrez Valdez OM. Desigualdad e inequidad social: resultados de la pandemia en México 2020–2021. ESECONOMIA. 2021;16(54):33–43. DOI:10.29201/eseconomia.v16i54.45.
Viboud C, Simonsen L, Fuentes R, Flores J, Miller MA, Chowell G. Global mortality impact of the 1957–1959 influenza pandemic. J Infect Dis. 2016;213(5):738–745. DOI:10.1093/infdis/jiv534.
Mena I, Nelson MI, Quezada-Monroy F, Dutta J, Cortes-Fernández R, Lara-Puente JH, et al. Origins of the 2009 H1N1 influenza pandemic in swine in Mexico. eLife. 2016;5:e16777. DOI:10.7554/eLife.16777.
Pan American Health Organization. Health in the Americas 2022: overview of the Region of the Americas in the context of the COVID-19 pandemic. Washington (DC): PAHO; 2022. https://iris.paho.org/handle/10665.2/56472
Martínez-Zavala B, Hegewisch-Taylor J, Arango-Angarita A, Barragán-Vázquez S, Rojas-Calderón H, Uribe-Carvajal R, et al. Escudos sociales y balas mágicas para el control de la epidemia por COVID-19 en México. Salud Publica Mex. 2022;64(2):218–224. DOI:10.21149/12923.
Castro MC, Wilson ME, Bloom DE. Disease and economic burdens of dengue. Lancet Infect Dis. 2017;17(3):e70–e78. DOI:10.1016/S1473-3099(16)30545-X.
Cabezas C, Vasconcelos PFC. Growing threat of emerging and reemerging diseases: arboviruses and vector-borne diseases in the Americas. Rev Peru Med Exp Salud Publica. 2024;41(1):4–6. DOI:10.17843/rpmesp.2024.411.13805.
Hartinger SM, Palmeiro-Silva YK, Llerena-Cayo C, Blanco-Villafuerte L, Escobar LE, Diaz A, et al. The 2023 Latin America report of the Lancet Countdown on health and climate change: the imperative for health-centred climate-resilient development. Lancet Reg Health Am. 2024;33:100746. DOI:10.1016/j.lana.2024.100746.
Del Carpio Orantes L, Aguilar Silva A. La cambiante dinámica epidemiológica del dengue en México. Med Interna Mex. 2024;40(6). DOI:10.24245/mim.v40iJulio.8621.
Mendoza-González MF. Perfil epidemiológico crítico de la enfermedad crónica no transmisible en México. Hacia Promoc Salud. 2025;30(1):67–82. DOI:10.17151/hpsal.2025.30.1.7.
Chandu VC, Marella Y, Panga GS, Pachava S, Vadapalli V. Measuring the impact of COVID-19 on mental health: a scoping review of the existing scales. Indian J Psychol Med. 2020;42(5):421–427. DOI:10.1177/0253717620946439.
Campodónico NM. Efectos en la salud mental en la población mexicana a partir de la pandemia por el COVID-19: una revisión sistemática. Veritas & Research. 2024;37. https://pure.udem.edu.mx/ws/portalfiles/portal/73764219/Veritas_2024.pdf
Frenk J, Gómez-Dantés O. The triple burden: disease in developing nations. Harv Int Rev. 2011;33:36. https://scholarship.miami.edu/esploro/outputs/journalArticle/The-Triple-Burden-Disease-in-Developing/991031718543902976
Barreto ML. Health inequalities: a global perspective. Cien Saude Colet. 2017;22(7):2097–2108. DOI:10.1590/1413-81232017227.02742017.
Secretaría de Salud (MX), Dirección General de Epidemiología. Boletín Epidemiológico: Sistema Nacional de Vigilancia Epidemiológica, Sistema Único de Información. México: Secretaría de Salud; 2025. https://www.gob.mx/salud/acciones-y-programas/direccion-general-de-epidemiologia-boletin-epidemiologico
Agudelo-Botero M, Dávila-Cervantes CA, Velasco-Calderón O, Giraldo-Rodríguez L. Divergences and gaps in life expectancy and health-adjusted life expectancy in Mexico: contribution analysis of the Global Burden of Disease Study 2019. PLoS One. 2023;18(11):e0293881. DOI:10.1371/journal.pone.0293881.
Gómez-Dantés H, Fullman N, Lamadrid-Figueroa H, Cahuana-Hurtado L, Darney B, Avila-Burgos L, et al. Dissonant health transition in the states of Mexico, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2016;388(10058):2386–2402. DOI:10.1016/S0140-6736(16)31773-1.
Chen Z, Tsui JL, Gutierrez B, Busch Moreno S, du Plessis L, Deng X, et al. COVID-19 pandemic interventions reshaped the global dispersal of seasonal influenza viruses. Science. 2024;386(6722):eadq3003. DOI:10.1126/science.adq3003.
Huang QS, Wood T, Jelley L, Jennings T, Jefferies S, Daniells K, et al. Impact of the COVID-19 nonpharmaceutical interventions on influenza and other respiratory viral infections in New Zealand. Nat Commun. 2021;12(1):1001. DOI:10.1038/s41467-021-21157-9.
Macías AE, Puentes-Rosas E, Velandia D, Morley D, Coudeville L, Baurin N. Real-world evidence of dengue burden on hospitals in Mexico: insights from the Automated Subsystem of Hospital Discharges (SAEH) database. Rev Invest Clin. 2019;71(3):168–177. DOI:10.24875/RIC.18002681.
Lugo-Radillo A, Mendoza-Cano O, Trujillo X, Huerta M, Ríos-Silva M, Guzmán-Esquivel J, et al. Assessing the burden of dengue during the COVID-19 pandemic in Mexico. Trop Med Infect Dis. 2023;8(4):232. DOI:10.3390/tropicalmed8040232.
Valdez-Santiago R, Villalobos-Hernández AL, Arenas-Monreal L, Flores K, Ramos-Lira L. Violencia en el hogar contra mujeres adultas durante el confinamiento por la pandemia de COVID-19 en México. Salud Publica Mex. 2021;63(6):782–788. DOI:10.21149/13244.
Trianni A, Oliveira e Souza R. Transforming mental health for pandemic recovery and social development: recommendations from the PAHO High-Level Commission on Mental Health and COVID-19. Lancet Reg Health Am. 2023;22:100527. DOI:10.1016/j.lana.2023.100527.
Basto-Abreu A, López-Olmedo N, Rojas-Martínez R, Aguilar-Salinas CA, Moreno-Banda GL, Carnalla M, et al. Prevalencia de prediabetes y diabetes en México: Ensanut 2022. Salud Publica Mex. 2023;65(Suppl):S163–S168. DOI:10.21149/14832.
Campos-Nonato I, Oviedo-Solís C, Vargas-Meza J, Ramírez-Villalobos D, Medina-García C, Gómez-Álvarez E, et al. Prevalencia, tratamiento y control de la hipertensión arterial en adultos mexicanos: resultados de la Ensanut 2022. Salud Publica Mex. 2023;65(Suppl):S169–S180. DOI:10.21149/14779.
Antonio-Villa NE, Bello-Chavolla OY, Fermín-Martínez CA, Ramírez-García D, Vargas-Vázquez A, Basile-Alvarez MR, et al. Diabetes subgroups and sociodemographic inequalities in Mexico: a cross-sectional analysis of nationally representative surveys from 2016 to 2022. Lancet Reg Health Am. 2024;33:100732. DOI:10.1016/j.lana.2024.100732.
Tausch A, Oliveira e Souza R, Martinez Viciana C, Cayetano C, Barbosa J, Hennis AJM. Strengthening mental health responses to COVID-19 in the Americas: a health policy analysis and recommendations. Lancet Reg Health Am. 2022;5:100118. DOI:10.1016/j.lana.2021.100118.
Kola L, Kumar M, Kohrt BA, Fatodu T, Olayemi BA, Adefolarin AO. Strengthening public mental health during and after the acute phase of the COVID-19 pandemic. Lancet. 2022;399(10338):1851–1852. DOI:10.1016/S0140-6736(22)00523-2.
Rivera Rivera L, Séris Martínez M, Reynales Shigematsu LM, Gómez García JA, Austria Corrales F, Toledano-Toledano F, et al. Violence against women during the COVID-19 pandemic in Mexico. Healthcare (Basel). 2023;11(3):419. DOI:10.3390/healthcare11030419.
Feng L, Zhang T, Wang Q, Xie Y, Peng Z, Zheng J, et al. Impact of COVID-19 outbreaks and interventions on influenza in China and the United States. Nat Commun. 2021;12:3249. DOI:10.1038/s41467-021-23440-1.
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